Cancer Biology Specialization Course Syllabus

Overview: This specialization provides a comprehensive introduction to cancer biology, integrating molecular mechanisms, genomic analysis, and clinical applications. Over approximately 14 weeks of part-time study, learners will explore the biological hallmarks of cancer, genetic and epigenetic drivers, diagnostic techniques, and modern therapies including immunotherapy. The course combines theoretical knowledge with hands-on bioinformatics exercises, preparing learners for advanced study or careers in oncology research. Each module builds foundational understanding while emphasizing real-world applications in cancer science.

Module 1: Introduction to Cancer Biology

Estimated time: 16 hours

• Study cancer epidemiology and global burden of disease
• Analyze multistep carcinogenesis models
• Explore cancer stem cell theory
• Examine case studies of common cancers

Module 2: Molecular Basis of Cancer

Estimated time: 16 hours

• Examine oncogenes and tumor suppressor genes
• Investigate DNA repair mechanisms
• Study epigenetic modifications in cancer
• Practice using the COSMIC mutation database

Module 3: Cancer Diagnosis and Therapy

Estimated time: 8 hours

• Compare imaging modalities (CT, MRI, PET)
• Evaluate chemotherapy and radiation mechanisms
• Analyze emerging immunotherapies
• Participate in virtual tumor boards

Module 4: Cancer Genomics

Estimated time: 16 hours

• Process next-generation sequencing data
• Identify actionable biomarkers
• Design targeted therapy plans
• Debate ethical dilemmas in precision oncology

Module 5: Research and Critical Analysis in Oncology

Estimated time: 12 hours

• Interpret cancer research literature critically
• Explore tumor microenvironment interactions
• Examine ethical issues in oncology research

Module 6: Final Project

Estimated time: 10 hours

• Deliverable 1: Analyze a real cancer genomics dataset using bioinformatics tools
• Deliverable 2: Evaluate molecular mechanisms underlying a selected cancer type
• Deliverable 3: Present diagnostic and therapeutic recommendations based on genomic findings

Prerequisites

• College-level biology background
• Familiarity with basic genetics and cell biology
• Basic statistics helpful but not required

What You'll Be Able to Do After

• Master the 10 biological hallmarks of cancer
• Understand genetic mutations driving tumor development
• Analyze cancer genomics data using bioinformatics tools
• Evaluate modern diagnostic and treatment approaches
• Interpret cancer research literature critically